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American Academy of Allergy Asthma & Immunology practice parameters do not support the use of any determination of IgG4 levels in the diagnosis and management of food allergies. The concept has become very popular on the internet as an alternative method to the more traditional method of skin testing. The companies that promote this idea seem almost trying to convince people that there is something wrong. In fact, specific IgG4 has some importance in defining a clinical improvement to an allergen, not a cause of allergies or asthma. Said plainly, IgG4 values do not mean you have an allergy.

So patients need to be careful about companies which are not run by medical doctors that suggest they have ways to uncover undiagnosed allergies.

From www.metametrix.com, they ask"What is an IgG4 response?" Their answer is that IgG4 antibodies are associated with non-atopic or "delayed" food reactions that can worsen or contribute to many different health problems life Rheumatoid Arthritis or Sinusitis. These reactions are considered "far more common" form of health problem than an IgE-mediated problem. Unfortunately, there is no basis for any of these claims, but it does certainly sounds convincing.

Their claims that these IgG4 reactions are more difficult to notice since they can occur hours or even days after consumption of an offending food is quite convenient because there is no way to diagnose this "illness".

A much more straight forward approach to the subject of food allergies can be found in a simple brochure from the AAAAI which is available for review or download. Click here for a readable, clear brochure from AAAAI.

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Please be careful about the use of IgG4 tests to measure allergy. They are expensive and not helpful in the least.

 

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